Jujube Versus Polyethylene Glycol for Maintenance Treatment of Pediatric Functional Constipation: A Randomized Clinical Trial

Background: Functional constipation (FC) is a common major problem in children. This study compared Jujube paste and polyethylene glycol (PEG) as laxative drugs children with FC. Ziziphus Jujuba Mill (Jujube) was selected according to traditional Iranian medicine because it native Iran large extent of Asia, safe easy access, acceptable taste Methods: randomized controlled clinical trial performed on 128 aged 2 12 FC Rome IV criteria. Patients were randomly divided into two groups PEG underwent four weeks treatment. The efficacy, safety, tolerability the oral product PEG. Results: Following therapy, all symptoms criteria improved significantly both (P < 0.05). In seven IV, effective even stronger reducing stool stiffness 0.0001). No hazardous side effect reported groups. Moreover, medication acceptance rate higher group receiving than Conclusions: pediatric has high nutritional value antioxidant properties, so can be substitute for